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Raw material introduction
Polygonum cuspidatum (scientific name: Reynoutria japonica Houtt.): Polygonaceae, Polygonum cuspidatum is a perennial herb. The rhizome is used for medicine, and has the effects of activating blood, removing blood stasis, smoothing menstruation, and relieving cough.
Chemical composition
Polygonum cuspidatum mainly contains emodin, chrysophal, rhein, physcion, and emodin- β- D-glucoside (physion-8- β- D-glucoside), emodin - 8 - monomethyl ether (Questin), resveratrol, resveratrol, resveratrol, resveratrol - 4 '- O-glucoside, quercetin, naphthoquinone, naphthyl glucoside, coumarin, polysaccharide, etc. It also contains Fallacinol, Chemical book Protocate chinocacid, Catechin, 2,5-dimethyl-7-hydrotryptophone, 7-hydroxy-4-methyl-5-methylcoumarin, cassia obtusifolia-8-O-D-glucoside, 2-methoxy-6-acetylmethyljuglone, flavanol glycoside, isoquercitrin), Glucoflorin β- Sitosterol（ β- Sitosterol), etc.
Pharmacological effects of extracts from Polygonum cuspidatum
The extracts of Polygonum cuspidatum have a wide range of pharmacological effects, including anti infection, anti inflammation, anti-oxidation, anti-tumor, metabolic regulation, organ protection, anti fibrosis, anti shock, etc. Among them, the effects of organ protection, anti shock, anti fibrosis, etc. may be related to the basic pharmacological actions of anti-oxidation, anti inflammation, etc., and the specific mechanism needs further discussion.
Polygonum cuspidatum has the effect of anti - virus, bacteria, fungi, parasites and other pathogenic microorganisms. Polygonum cuspidatum has inhibitory effect on HIV, HBV, EBV, influenza virus and other viruses. For example, Polygonum cuspidatum can induce interferon through toll like receptor 9 β To inhibit influenza virus replication.
Polygonum cuspidatum has a wide range of antibacterial effects. The antibacterial spectrum includes common bacteria such as Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus A and even hospital resistant bacteria. Its main antibacterial components are stilbenes and anthraquinones. The mechanism of action may be to destroy the integrity of bacterial cell membrane, and some components may even play the role of bacterial DNA primer enzyme inhibitors.
In addition, Polygonum cuspidatum has antifungal effect. Studies have confirmed that Polygonum cuspidatum can inhibit trichophyton rubrum, candida albicans, pigmented mold Pei, apple rot fungus and other fungi. Recent studies have found that Polygonum cuspidatum also has the effect of anti parasites. The experiment shows that veratrol alone or in combination with amphotericin has the effect of anti Leishmania amazonicum.
Product analysis
SPECIFICATION | ||
Product Name:Polygonum cuspidatum extract sample | Origin of Material: china | |
Botanical Source:Polygonum | Part Used:rhizome | |
ANALYSIS | SPECIFICATION | REMARK |
Appearance | white powder | |
Odor | Characteristic | Organoleptic |
Taste | Characteristic | Organoleptic |
Sieve Analysis | 95% pass 80 mesh | |
Loss on Drying | ≤5% | 2 hours at 105°C |
Bulk Density | 40-60g/100ml | |
Total Ash | ≤5% | |
Heavy Metals | ≤10ppm | EP2.4.8 |
As | ≤1ppm | ICP-MS |
Pb | ≤3ppm | ICP-MS |
Microbiological Test | ||
Total Plate Count | ≤10000cfu/g | |
Yeast & Mold | ≤1000cfu/g | |
E.Coli E | Negative | |
Salmonella | Negative | |
Storage: In a cool & dry place. Keep away from strong light and heat. | ||
Shelf Life: 2 years when properly stored. | ||
* There is likely to be minor color variation from batch to batch due to geographical(origin) and seasonal variations of the material. | ||
Polygonum cuspidatum extract certificate
Factory
Raw material introduction
Polygonum cuspidatum (scientific name: Reynoutria japonica Houtt.): Polygonaceae, Polygonum cuspidatum is a perennial herb. The rhizome is used for medicine, and has the effects of activating blood, removing blood stasis, smoothing menstruation, and relieving cough.
Chemical composition
Polygonum cuspidatum mainly contains emodin, chrysophal, rhein, physcion, and emodin- β- D-glucoside (physion-8- β- D-glucoside), emodin - 8 - monomethyl ether (Questin), resveratrol, resveratrol, resveratrol, resveratrol - 4 '- O-glucoside, quercetin, naphthoquinone, naphthyl glucoside, coumarin, polysaccharide, etc. It also contains Fallacinol, Chemical book Protocate chinocacid, Catechin, 2,5-dimethyl-7-hydrotryptophone, 7-hydroxy-4-methyl-5-methylcoumarin, cassia obtusifolia-8-O-D-glucoside, 2-methoxy-6-acetylmethyljuglone, flavanol glycoside, isoquercitrin), Glucoflorin β- Sitosterol（ β- Sitosterol), etc.
Pharmacological effects of extracts from Polygonum cuspidatum
The extracts of Polygonum cuspidatum have a wide range of pharmacological effects, including anti infection, anti inflammation, anti-oxidation, anti-tumor, metabolic regulation, organ protection, anti fibrosis, anti shock, etc. Among them, the effects of organ protection, anti shock, anti fibrosis, etc. may be related to the basic pharmacological actions of anti-oxidation, anti inflammation, etc., and the specific mechanism needs further discussion.
Polygonum cuspidatum has the effect of anti - virus, bacteria, fungi, parasites and other pathogenic microorganisms. Polygonum cuspidatum has inhibitory effect on HIV, HBV, EBV, influenza virus and other viruses. For example, Polygonum cuspidatum can induce interferon through toll like receptor 9 β To inhibit influenza virus replication.
Polygonum cuspidatum has a wide range of antibacterial effects. The antibacterial spectrum includes common bacteria such as Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus A and even hospital resistant bacteria. Its main antibacterial components are stilbenes and anthraquinones. The mechanism of action may be to destroy the integrity of bacterial cell membrane, and some components may even play the role of bacterial DNA primer enzyme inhibitors.
In addition, Polygonum cuspidatum has antifungal effect. Studies have confirmed that Polygonum cuspidatum can inhibit trichophyton rubrum, candida albicans, pigmented mold Pei, apple rot fungus and other fungi. Recent studies have found that Polygonum cuspidatum also has the effect of anti parasites. The experiment shows that veratrol alone or in combination with amphotericin has the effect of anti Leishmania amazonicum.
Product analysis
SPECIFICATION | ||
Product Name:Polygonum cuspidatum extract sample | Origin of Material: china | |
Botanical Source:Polygonum | Part Used:rhizome | |
ANALYSIS | SPECIFICATION | REMARK |
Appearance | white powder | |
Odor | Characteristic | Organoleptic |
Taste | Characteristic | Organoleptic |
Sieve Analysis | 95% pass 80 mesh | |
Loss on Drying | ≤5% | 2 hours at 105°C |
Bulk Density | 40-60g/100ml | |
Total Ash | ≤5% | |
Heavy Metals | ≤10ppm | EP2.4.8 |
As | ≤1ppm | ICP-MS |
Pb | ≤3ppm | ICP-MS |
Microbiological Test | ||
Total Plate Count | ≤10000cfu/g | |
Yeast & Mold | ≤1000cfu/g | |
E.Coli E | Negative | |
Salmonella | Negative | |
Storage: In a cool & dry place. Keep away from strong light and heat. | ||
Shelf Life: 2 years when properly stored. | ||
* There is likely to be minor color variation from batch to batch due to geographical(origin) and seasonal variations of the material. | ||
Polygonum cuspidatum extract certificate
Factory
