Green Tea Extract Tea Polyphenols

Tea Extract

There are two main types of tea extracts in the skin care field: green tea extract and black tea extract. For unfermented green tea, fresh green tea extract (GTE) is rich in polyphenols (collectively: green tea polyphenols, abbreviated as GTPs/GTP/GTPP), carrying the banner of antioxidant. After fermentation, such as black tea, black tea polyphenols, mainly composed of thearubigin, theaflavin and theafuscin, play an antioxidant role. Green tea polyphenols (GTPs) are mixtures with good antioxidant effects, which are composed of catechins, proanthocyanidins, phenolic acids and flavonoids. Catechins are composed of eight active substances, which are actually various chemical combinations of catechins and gallic acid and optical isomers

Pharmacological action

1. Green tea extract tea polyphenols (GTPs) can reduce erythema caused by ultraviolet light

A study showed that green tea polyphenols had a good inhibitory effect on erythema caused by ultraviolet light. Six volunteers were smeared with 0.2 mL of GTPs with a concentration ranging from 1% to 10% on their back skin 30 minutes in advance, and then exposed to a certain dose of ultraviolet radiation from simulated sunlight. After 24, 48 and 72 hours of radiation, it was found that with the gradual increase of green tea polyphenols concentration, the degree of erythema decreased significantly, indicating that green tea polyphenols (GTPs) had a good inhibitory effect on erythema caused by ultraviolet (UVR) radiation.

2. Green tea extract tea polyphenols (GTPs) can reduce inflammation caused by ultraviolet light

In the article on photoaging, it is mentioned that ROS caused by ultraviolet radiation can activate transcription factor (NF- κ B) , causing a series of cellular inflammation, which will aggravate the decomposition of extracellular matrix (ECM) and cause photoaging. EGCG in green tea polyphenols has good inhibition and activation of green transforming factor NF in some animal and human cell studies- κ B activity, with certain anti-inflammatory effect, can protect skin cells from the adverse effects of ultraviolet radiation, thus achieving the effect of anti photoaging.

3. Green tea extract tea polyphenols (GTPs) can reduce the damage of ultraviolet rays to human cell DNA

UVB in ultraviolet ray can directly cause DNA damage of skin cells, and UVA can indirectly cause DNA damage of skin cells through ROS. Damage to the DNA of skin cells will cause cell inflammation and apoptosis of skin cells, resulting in the decomposition of extracellular matrix. In the long run, the macroscopic manifestations are the loss of skin collagen and the formation of wrinkles. In severe cases, skin cancer and melanoma can be formed.

Therefore, it is of great significance to reduce the damage of UV to skin cell DNA as far as possible to prevent photoaging. In a scientific study of six female and four male non-smoking volunteers, volunteers were asked to abstain from alcohol for 24 hours before the experiment began. Before the experiment, take 5ml of blood from each volunteer, and then let the volunteers drink 3 cups of green tea drinks (2.5g pure green tea bags are boiled in boiling water for 2 minutes). After drinking tea for 40 minutes, another blood sample was taken from the volunteers. The blood sample shall be treated to a certain extent, and then exposed to the xenon lamp (providing ultraviolet visible light) for a certain time for sampling and analysis. Some experimental results are shown in Fig. 6, which shows that EGCG has a significant inhibitory effect on cell DNA damage caused by ultraviolet light. Because EGCG can inhibit DNA damage, it is not difficult to understand the anti-cancer effect of green tea.

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