Views: 21 Author: Site Editor Publish Time: 2017-11-24 Origin: Site
In recent years, paeoniflorin as the main active ingredient in commonly used Chinese medicine Paeonia has been achieving more and more attention by scholars at domestic and abroad, and studies on the drug action of paeoniflorin also have been getting more and more. After further research, it is found that paeoniflorin has a variety of biological effects of lowering blood viscosity, anti-platelet aggregation, dilating blood vessels, improving microcirculation, anti-oxidation, anticonvulsant and so on.
1. Dilate blood vessels
Paeoniflorin can dilate coronary arteries, increase coronary blood flow, combat acute myocardial ischemia, and lower blood pressure.
2. Protect against cerebral ischemia
Paeoniflorin was found to have protective effects on cerebral edema, blood-brain barrier and regional cerebral blood flow after cerebral ischemia. And it also can promote the recovery of early cerebral ischemia-reperfusion.
3. Antithrombotic effect
Paeoniflorin can improve anti-high-fat and high cholesterol-induced thrombosis effect.
4. Anti-platelet aggregation
Platelet aggregation is an important "culprit" causing all kinds of cardiovascular and cerebrovascular diseases. Paeoniflorin have different degrees of inhibition on ADP and collagen-induced platelet aggregation.
5. Anti-hyperlipidemic effect
Researchers at Ulsan University in South Korea found that Paeoniflorin showed a significant reduction in total cholesterol, low density lipoprotein and triglyceride levels
By intravenous injection of paeoniflorin, Taiwanese medical workers found that paeoniflorin can reverse guanethidine-induced hypotension by activating adenosine A1 receptors in the brain of Wistar rats.
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